Mass Cytometry Marker Panel Extension

High-dimensional mass cytometry (CyTOF) permits the simultaneous measurement of many cellular markers, providing a system-wide view of immune phenotypes at the single-cell level1. Yet, the maximum number of markers that can be measure simultaneously is limited to ~50 due to several technical challenges. We propose a new method to integrate CyTOF data from several marker panels that include an overlapping set of markers, allowing for a deeper interrogation of the cellular composition of the immune system.

Resources

Preprint

Citation

Tamim Abdelaal, Ahmed Mahfouz, Thomas Höllt, Vincent van Unen, Frits Koning, Boudewijn Lelieveldt, and Marcel Reinders. Mass Cytometry Marker Panel Extension. Poster Presentation, Keystone Symposia on Molecular and Cellular Biology; Single Cell Omics, Stockholm, Swe, 2017.

BibTeX

@misc{ bib:2017_ksomics_tamim,
    author = {Tamim Abdelaal and Ahmed Mahfouz and Thomas H{\"o}llt and Vincent van Unen and Frits Koning and Boudewijn Lelieveldt and Marcel Reinders},
    title = { Mass Cytometry Marker Panel Extension },
    howpublished = { Poster presentation at Poster Presentation, Keystone Symposia on Molecular and Cellular Biology; Single Cell Omics, Stockholm, Swe },
    year = { 2017 },
}